Apoptosis, or cell death, can be pathological, a sign of disease and damage, or physiological, a process essential for n. Jude childrens research hospital anthony letai, danafarber cancer institute we are pleased to announce the eleventh meeting on cell death, to be held at cold spring harbor laboratory from tuesday evening, september 15. Once logged in, you can add biography in the database. In means to an end, douglas green provides a clear and comprehensive view.
Cell death september 15 19, 2015 abstract deadline. Green frontmatter more informatio n cambridge university press cambridge, new york,melbourne, madrid, cape town, singapore,sao paulo,delhi, tokyo,mexico city. Doherty endowed chair of immunology at st jude childrens research hospital. His most recent book is apoptosis and other cell death. It is divided into three sections for convenient and easy reading. Cambridge core molecular biology, biochemistry, and structural biology apoptosis by douglas r.
This book, with contributions from experts in the field. Cambridge university press 32avenueofthe americas, new york, ny 1002473,usa. Apoptosis, or cell death, can be pathological, a sign of disease and damage, or physiological, a process essential for normal health. Means to an end the companion site to the new book on cell. David andrews, university of toronto, canada douglas green, st. Taking a bottomup approach, he starts with the enzymes that perform the execution process a family of proteases termed caspases and examines their cellular targets and the ways in which they are activated. In this second edition of douglas greens essential book on cell death, green retains the bottomup approach of the first edition, starting with the enzymes that carry out the execution caspases and their cellular targets before examining the machinery that. Page 4 of 26 due to its importance in such various biological processes, programmed cell death is a widespread phenomenon, occuring in all kinds of metazoans tittel, 2000 such as in mammals, insects. Apoptosis and other means to an end, second edition by douglas r. Jude childrens research hospital department of immunology and peter c. The significance of apoptosis the development and maintenance of multicellular biological systems depends on a sophisticated interplay between the cells forming the organism, it sometimes even seems to involve an altruistic behaviour of individual cells in favour of the organism as a whole. Jude, is one of four recipients of the 2019 wilbur lucius cross medal for alumni achievement from the yale graduate school of arts and sciences green earned his bachelor of science degree from yale in 1977. Jude, is one of four recipients of the 2019 wilbur lucius cross medal for alumni achievement from the yale graduate school of arts and sciences.
In means to an end, douglas green provides a clear and comprehensive view of apoptosis and other cell death mechanisms. Cover of the second edition of the book cell death. This step allows the release of proapoptotic proteins from the mitochondrial intermembrane space into the cytoplasm. Green 2011, hardcover at the best online prices at ebay. A fundamental step in the commitment to apoptosis via the intrinsic pathway is mitochondrial outer membrane permeabilization momp. Apoptosis and other cell death mechanisms, highlights discoveries of the past 30 years on the mechanisms that control programmed cell death.
Cold spring harbor laboratory press, 2011 science 220 pages. Apoptosis and other means to an end, second edition author. Green states in the preface that this book is neither a monograph, nor an historical account, nor an exhaustive description of a. This pathological dysregulation of cell death can be. The second section which comprises a single solitary chapter looks at apoptosis in normal physiology during bone resorption under mechanical. The first section explores the different processes of cell death and. The second section which comprises a single solitary chapter looks at apoptosis in normal physiology during bone resorption under.
Green, 9780521886567, available at book depository with free delivery worldwide. Book description apoptosis, or cell death, can be pathological, a sign of disease and damage, or physiological, a process essential for normal health. In this second edition of douglas greens essential book on cell death, green retains the bottomup approach of the first edition, starting with the enzymes that. The book is organized into three convenient sections.
Choice as a leader in the field of cell death since the late 1980s, dr. Means to an end the companion site to the new book on. He has been chair of the department of immunology at st. The control of mitochondrial apoptosis by the bcl2 family. Nov 24, 2010 in his new book means to an end, doug green provides a clear and comprehensive view of apoptosis and other death mechanisms. Bok is a noncanonical bcl2 family effector of apoptosis. Greens contribution has been pivotal, particularly in defining the process of activationinduced apoptosis in t cellswe cannot do better than echo the words of martin raff, one of the founders of the cell death field, in his foreword. Apoptosis is essential for survival of the body as a whole and has critical roles in various developmental processes and the immune system. Doug green is a great writer and makes apoptosis, necrosis, autophagy, and other.
Physiology and pathology apoptosis, or cell death, can be pathological, a sign of disease and damage, or physiological, a read online books at. Douglas green born 1955, american biologist, author world. In this second edition of douglas greens essential book on cell death, green retains the bottomup approach of the first edition, starting with the enzymes that carry out the execution caspases and their cellular targets before examining the machinery that connects them to signals that cause cell death. His research has focused on the process of active cell death and cell survival, extending from the role of cell death in cancer regulation and immune responses in the whole organism to the molecular events directing the death of the cell. He examines the enzymes that perform the execution caspases and the molecular machinery that links their activation to signals that cause cell death, emphasizing the importance of bcl2 proteins and cytochrome c. Douglas green born 1955, american biologist, author. To see what your friends thought of this book, please sign up. Kindle books kindle unlimited prime reading bestsellers kindle daily deal kindle monthly deals free kindle reading apps buy a kindle content and devices kindle support. The book is thus of great use to all biologists interested in how cells function in. Apoptosis and other cell death mechanisms, by douglas r. Greens 40 research works with 7,640 citations and 986 reads, including.
Methods and protocols, second edition, expert researchers describe the techniques to best investigate the critical steps involved in the apoptotic process. The bcl2 family member bok offers a path to mitochondrial outer membrane permeabilization. Apoptosis and other means to an end, second edition. Presented from several different research perspectives, the volume contains sections covering detection of apoptosis, detection of nonapoptotic cell death, modifications of. Everyday low prices and free delivery on eligible orders. Apoptosis and other cell death mechanisms by douglas r. Doug green is the author of the new book on cell death means to an end. In means to an end, douglas green provides a clear and comprehensive view of apoptosis and. This book looks at the latest research studies on apoptosis in medicine. Greens contribution has been pivotal, particularly in defining the process of activationinduced apoptosis in t cellswe cannot do better than echo the words of martin raff, one of the founders of the cell death field, in his. Green published by cold spring harbor laboratory press 500 sunnyside blvd, woodbury, ny 117972924, usa. See all 9 formats and editions hide other formats and editions.
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